PubMed

Täydentävä – vaihtoehtoinen lääketiede (CAM) ja satunnaiskontrolloitu tutkimus (RCT) PubMed -tietokannassa

Satunnaiskontrolloitu tutkimus (RCT) on yleisimmin käytetty tieteellinen tutkimusmalli testattaessa terveydenhuollon palveluita tai terveyteen liittyvän teknologian tehoa ja vaikuttavuutta. Nimensä mukaisesti RCT:ssä tutkittavat jaetaan satunnaisesti eri hoitoihin. Kun tutkittavien määrä on riittävä, ovat sekä tunnetut että tuntemattomat tekijät sekoittuneet tasaisesti eri hoitoryhmissä.

Medline on tärkein kansainvälinen lääketieteellinen tietokanta, jota ylläpitää National Library of Medicine (NLM) USA:ssa. Se sisältää aikakausjulkaisujen artikkeliviitteitä, joita tietokantaan lisätään päivittäin. Tietokanta on käytettävissä ilmaiseksi PubMed -nimisenä. PubMed-tietokannassa on linkkejä myös kokonaisiin lehtiin ja artikkeliteksteihin. Osa näistä lehdistä voi olla käyttöoikeudeltaan rajoitettuja. Medline sisältää yli 18 miljoonaa otetta vuodesta 1948.

Hakuyhdistelmällä ”complementary and alternative medicine + randomized controlled trials” löytyi yli 400 artikkelia( 13.3.09). Seuraavassa on poimintoja RCT –tutkimuksista tai yhteenvetotutkimuksista, joissa RCT on mukana:

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Bibliographical investigation of complementary alternative medicines for osteoarthritis and rheumatoid arthritis.
Kikuchi M, Matsuura K, Matsumoto Y, Inagaki T, Ueda R.
Geriatr Gerontol Int. 2009 Mar;9(1):29-40.
PMID: 19260977 [PubMed - in process]
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A randomised controlled trial of the Neuro Emotional Technique (NET) for childhood Attention Deficit Hyperactivity Disorder (ADHD): a protocol. 
Karpouzis F, Pollard H, Bonello R.
Trials. 2009 Jan 27;10:6.
PMID: 19173743 [PubMed - in process]
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Evidence-based effect size estimation: an illustration using the case of acupuncture for cancer-related fatigue. 
Johnston MF, Hays RD, Hui KK.
BMC Complement Altern Med. 2009 Jan 13;9:1.
PMID: 19144128 [PubMed - in process]
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Acupuncture for obesity: a systematic review and meta-analysis. 
Cho SH, Lee JS, Thabane L, Lee J.
Int J Obes (Lond). 2009 Feb;33(2):183-96. Epub 2009 Jan 13.
PMID: 19139756 [PubMed - in process]
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Acupuncture, or non-directive counselling versus usual care for the treatment of depression: a pilot study. 
Schroer S, Macpherson H.
Trials. 2009 Jan 9;10:3.
PMID: 19134170 [PubMed - in process]
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Chiropractic management of fibromyalgia syndrome: a systematic review of the literature. 
Schneider M, Vernon H, Ko G, Lawson G, Perera J.
J Manipulative Physiol Ther. 2009 Jan;32(1):25-40.
PMID: 19121462 [PubMed - in process]
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Effect of fish oil on arrhythmias and mortality: systematic review. 
León H, Shibata MC, Sivakumaran S, Dorgan M, Chatterley T, Tsuyuki RT.
BMJ. 2008 Dec 23;337:a2931. doi: 10.1136/bmj.a2931. Review. 
PMID: 19106137 [PubMed - indexed for MEDLINE]
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Frankincense: systematic review. 
Ernst E.
BMJ. 2008 Dec 17;337:a2813. doi: 10.1136/bmj.a2813. Review.
PMID: 19091760 [PubMed - indexed for MEDLINE]
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Study Protocol: effects of acupuncture on hot flushes in perimenopausal and postmenopausal women - a multicenter randomized clinical trial. 
Kim KH, Kang KW, Jung HJ, Park JE, Jung SY, Choi JY, Choi SM.
Trials. 2008 Dec 3;9:70.
PMID: 19055763 [PubMed - in process]
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Recruitment and enrollment for the simultaneous conduct of 2 randomized controlled trials for patients with subacute and chronic low back pain at a CAM research center. 
Hondras MA, Long CR, Haan AG, Spencer LB, Meeker WC.
J Altern Complement Med. 2008 Oct;14(8):983-92.
PMID: 18990046 [PubMed - indexed for MEDLINE]
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Disclosure to physicians of CAM use by breast cancer patients: findings from the Women's Healthy Eating and Living Study. 
Saxe GA, Madlensky L, Kealey S, Wu DP, Freeman KL, Pierce JP.
Integr Cancer Ther. 2008 Sep;7(3):122-9.
PMID: 18956493 [PubMed - indexed for MEDLINE]
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Mistletoe Preparation Iscador: Are there Methodological Concerns with Respect to Controlled Clinical Trials? 
Ziegler R.
Evid Based Complement Alternat Med. 2009 Mar;6(1):19-30. Epub 2007 Oct 4.
PMID: 18955241 [PubMed - in process]
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Effectiveness of osteopathy in the cranial field and myofascial release versus acupuncture as complementary treatment for children with spastic cerebral palsy: a pilot study. 
Duncan B, McDonough-Means S, Worden K, Schnyer R, Andrews J, Meaney FJ.
J Am Osteopath Assoc. 2008 Oct;108(10):559-70.
PMID: 18948639 [PubMed - indexed for MEDLINE]
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Relaxation for depression. 
Jorm AF, Morgan AJ, Hetrick SE.
Cochrane Database Syst Rev. 2008 Oct 8;(4):CD007142. Review.
PMID: 18843744 [PubMed - indexed for MEDLINE]
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St John's wort for major depression. 
Linde K, Berner MM, Kriston L.
Cochrane Database Syst Rev. 2008 Oct 8;(4):CD000448. Review. 
PMID: 18843608 [PubMed - indexed for MEDLINE]
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An evidence-based review of yoga as a complementary intervention for patients with cancer. 
Smith KB, Pukall CF.
Psychooncology. 2008 Sep 26. [Epub ahead of print]
PMID: 18821529 [PubMed - as supplied by publisher]
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Benefits of fish oil supplementation in hyperlipidemia: a systematic review and meta-analysis. 
Eslick GD, Howe PR, Smith C, Priest R, Bensoussan A.
Int J Cardiol. 2008 Sep 5. [Epub ahead of print]
PMID: 18774613 [PubMed - as supplied by publisher]
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